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Sunday, April 3, 2011

DERMATOPHYTES

This large group of fungi infect keratinised tissues and are responsible for ringworm of the body and scalp,
 'dhobi's itch' in the inguinal folds, and infection of the hair and nails. Trichophytum rubrum is the commonest cause and most difficult to treat.
Tinea imbricata (T.concentricum), characterised by multiple concentric rings, causes widespread disabling infections in some Pacific Islands  and in S.E.Asia. T.schoenleinii produces a mass of creamy white material, with an offensive odour, on the scalp, known as favus. Many deramatophytes are primarily parasites of domestic and farm animals.
Management
Dermatophytes are treated with topical antifungal ointments if mild, or if severe with griseofulvin 500 mg twice daily or ketoconazole 200-400 mg daily, by mouth.

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