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Tuesday, March 15, 2011


This is most commonly caused by the ingestion of aspirin, anti-inflammatory drugs and probably alcohol. It is also caused by the regurgitation of bile into the stomach, especially after gastric surgery.
 Macroscopically, there is engorgement of the mucosa with oedema and erosion or an acute hemorrhagic gastritis. Microscopically there is loss of the surface epithelium, hyperaemia and some infiltration with inflammatory cells.
Clinical features
Acute gastritis may be asymptomatic. In some patients there is anorexia, nausea, epigastric pain and heart burn. If gastritis persists, a slow loss of blood may lead to anaemia. The condition is diagnosed by gastroscopy.
Drug consumption should be reviewed with a view to omitting or reducing drugs which are known to cause gastric mucosal damage. Alcohol should be avoided.

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